67.5 B-
Tirzepatide
Also known as: Mounjaro, Zepbound
FDA Approved Research Chemical
Research Evidence 90.0/100
Safety Profile 45.0/100
79 Clinical Trials
Unknown: 9 PHASE4: 13 PHASE3: 8 PHASE2, PHASE3: 2 PHASE2: 26 PHASE1, PHASE2: 2 PHASE1: 6 NA: 11 EARLY_PHASE1: 2
- Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity Unknown Phase NOT_YET_RECRUITING Radboud University Medical Center
- Safety and Effectiveness of Tirzepatide in Patients With Obesity at Hospital de Clínicas, Paraguay Unknown Phase NOT_YET_RECRUITING LABORATORIOS INDUFAR
- GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound Unknown Phase RECRUITING Medical University of South Carolina
- INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD) Unknown Phase ACTIVE_NOT_RECRUITING Brigham and Women's Hospital
- Spartina® (Tirzepatide) Effectiveness and Safety Evaluation Unknown Phase RECRUITING Cinnagen
Showing 5 of 79 trials.
20 Research Papers
- Efficacy of tirzepatide, lanifibranor, and resmetirom in metabolic dysfunction-associated steatotic liver disease: a meta-analysis of high-quality randomized controlled trials. Intern Emerg Med Review
- Childhood Obesity and Cardiac Risk in Youth: Emerging Challenges Toward 2050. Clin Nutr ESPEN Review
- Preoperative GLP-1 Receptor Agonists and Thromboinflammatory Markers in Patients Undergoing Abdominoplasty: A Prospective Monocentric Study. Aesthetic Plast Surg unknown
- Real-World Clinical Evidence of Tirzepatide for Metabolic Abnormalities in Subjects With Type 2 Diabetes: The Multicenter Retrospective Observational Hokkaido-TZP Study. Diabetes Obes Metab unknown
- Estimating the True MACE Benefits From Tirzepatide in SURPASS-CVOT Using an Imputed Placebo Analysis of REWIND. Diabetes Care unknown
Showing 5 of 20 papers by citation count.
FDA Data
Not FDA-Approved
Tirzepatide has not been evaluated by the FDA for safety or efficacy. It is not approved for human therapeutic use in the United States.
Frequently Asked Questions
Is Tirzepatide FDA approved?
No, Tirzepatide has not been approved by the FDA for human therapeutic use. It is sold as a research chemical.
How many clinical trials has Tirzepatide been studied in?
Tirzepatide has been studied in 79 registered clinical trials. CheckPeptides tracks phase, status, and sponsor data for each trial.
What is the trust score for Tirzepatide?
Tirzepatide has a CheckPeptides trust score of 67.5/100 (grade: B-). This score is based on clinical trial volume, research paper quality, FDA data, and evidence classification.
Last verified: April 7, 2026
Quick Facts
- Classification
- GLP-1/GIP dual receptor agonist
- Molecular Weight
- 4813.0 Da
- PubChem
- CID 166567236 ↗
- Regulatory Status
- N/A
Score Breakdown
Research Evidence 90.0/100
Safety Profile 45.0/100
Evidence Summary
- Clinical Trials
- 79
- Research Papers
- 20
- Trust Score
- 67.5/100
- Grade
- B-