70.0 B
Pentosan Polysulfate
Also known as: PPS, Elmiron
Strong Clinical Evidence Research Chemical
Research Evidence 90.0/100
Safety Profile 50.0/100
71 Clinical Trials
Unknown: 9 PHASE4: 3 PHASE3: 16 PHASE2, PHASE3: 5 PHASE2: 8 PHASE1, PHASE2: 3 NA: 25 EARLY_PHASE1: 2
- IMPULS-NRW: Telemedicine in Specialized Outpatient Palliative Care Unknown Phase ACTIVE_NOT_RECRUITING University Hospital Muenster
- "Turkish Validation of the Respiratory Distress Observation Scale in Palliative Care" Unknown Phase COMPLETED Istinye University
- Integrative and Complementary Therapy for Episodic Migraine and Tension-type Headache Unknown Phase NOT_YET_RECRUITING Kliniken Essen-Mitte
- Treatment and Duration Effect of Pentosan Polysulfate Sodium (PPS) in Participants With Knee Osteoarthritis Pain Unknown Phase COMPLETED Paradigm Biopharmaceuticals Ltd.
- An Observational Study, Called DEAR, to Learn More About Treatment With Darolutamide, Enzalutamide and Apalutamide in Men With Non-metastatic Castration-resistant Prostate Cancer in Real World Settings Unknown Phase COMPLETED Bayer
Showing 5 of 71 trials.
20 Research Papers
- Variation In Medicaid And Medicare Payment Rates To Community Health Centers, 2023. Health Aff (Millwood) unknown
- Life cycle assessment of a wood-aluminium window according to European norms. Sci Rep unknown
- Cell type-specific transcriptional features associated with gray matter volume alterations in schizophrenia with predominantly negative symptoms. Asian J Psychiatr unknown
- Late Development of Clinically Apparent Pentosan Polysulfate Maculopathy after Drug Cessation. Retin Cases Brief Rep unknown
- Influence of cognitive functions on central auditory processing tests in university students. Codas unknown
Showing 5 of 20 papers by citation count.
FDA Data
Not FDA-Approved
Pentosan Polysulfate has not been evaluated by the FDA for safety or efficacy. It is not approved for human therapeutic use in the United States.
Frequently Asked Questions
Is Pentosan Polysulfate FDA approved?
No, Pentosan Polysulfate has not been approved by the FDA for human therapeutic use. It is sold as a research chemical.
How many clinical trials has Pentosan Polysulfate been studied in?
Pentosan Polysulfate has been studied in 71 registered clinical trials. CheckPeptides tracks phase, status, and sponsor data for each trial.
What is the trust score for Pentosan Polysulfate?
Pentosan Polysulfate has a CheckPeptides trust score of 70.0/100 (grade: B). This score is based on clinical trial volume, research paper quality, FDA data, and evidence classification.
Last verified: April 7, 2026
Quick Facts
- Classification
- Semi-synthetic polysaccharide
- Regulatory Status
- N/A
Score Breakdown
Research Evidence 90.0/100
Safety Profile 50.0/100
Evidence Summary
- Clinical Trials
- 71
- Research Papers
- 20
- Trust Score
- 70.0/100
- Grade
- B