77.5 B+
LL-37
Also known as: Cathelicidin, CAMP
Strong Clinical Evidence Research Chemical
Research Evidence 90.0/100
Safety Profile 65.0/100
128 Clinical Trials
Unknown: 27 PHASE4: 10 PHASE3: 13 PHASE2, PHASE3: 2 PHASE2: 21 PHASE1, PHASE2: 3 PHASE1: 4 NA: 46 EARLY_PHASE1: 2
- Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid Unknown Phase NOT_YET_RECRUITING Recep Tayyip Erdogan University
- Intermittent-Hypoxia Inhibits Neutrophil Extracellular Traps Formation: Role of Cathelicidins Unknown Phase NOT_YET_RECRUITING Kun-Ta Chou
- Multifaceted Analysis of the Adaptation of Rowers in the Process of Sports Training Unknown Phase COMPLETED Poznan University of Physical Education
- Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus Unknown Phase ACTIVE_NOT_RECRUITING Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
- Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children Unknown Phase COMPLETED Bezmialem Vakif University
Showing 5 of 128 trials.
20 Research Papers
- Molecular interaction modes of the host-defense peptide cathelicidin LL-37 and its mutants dictate diverse antimicrobial activities. Nanoscale unknown
- Medical humanities: An alliance or an aberration? Commun Med unknown
- Manipulation of regulators of morphogenesis is not sufficient to render a Candida albicans colonizer strain pathogenic. mBio unknown
- Can improved handwashing infrastructure and soap change behavior? findings from a randomized control study in the Dadaab refugee camp in Kenya. Confl Health unknown
- Antimicrobial Peptide WK-13-3D Inhibits Japanese Encephalitis Virus Infection by Interacting with Viral Particles, Potentially Targeting the Envelope Protein. Antiviral Res unknown
Showing 5 of 20 papers by citation count.
FDA Data
Not FDA-Approved
LL-37 has not been evaluated by the FDA for safety or efficacy. It is not approved for human therapeutic use in the United States.
Frequently Asked Questions
Is LL-37 FDA approved?
No, LL-37 has not been approved by the FDA for human therapeutic use. It is sold as a research chemical.
How many clinical trials has LL-37 been studied in?
LL-37 has been studied in 128 registered clinical trials. CheckPeptides tracks phase, status, and sponsor data for each trial.
What is the trust score for LL-37?
LL-37 has a CheckPeptides trust score of 77.5/100 (grade: B+). This score is based on clinical trial volume, research paper quality, FDA data, and evidence classification.
Last verified: April 7, 2026
Quick Facts
- Classification
- Host defence / antimicrobial peptide
- Molecular Weight
- 4493.0 Da
- PubChem
- CID 16198951 ↗
- Regulatory Status
- N/A
Score Breakdown
Research Evidence 90.0/100
Safety Profile 65.0/100
Evidence Summary
- Clinical Trials
- 128
- Research Papers
- 20
- Trust Score
- 77.5/100
- Grade
- B+